Diphtheria, Tetanus, Pertussis, and Hib Vaccine
In Canadian childhood vaccination programs, vaccines against diphtheria, tetanus, pertussis (whooping cough), polio and Haemophilus (a bacterial infection) are administered as one shot in a vaccine with the trade name, Pediacel®. An alternate vaccine being offered has a sixth component against hepatitis B. Since it eliminates any need for the single hepatitis B vaccine, one of the first four vaccines injected at 2 months, Public Health hopes this vaccine, Infanrix hexa™, will encourage more parents to opt for vaccination. What’s certain is that this vaccine will make it even more difficult for parents who wish to consent to only one or two single vaccines to do so. Although not disclosed in its monograph, the polio viruses of Infanrix hexa™ are cultured on aborted human foetal tissue.
Pediacel®, unlike its predecessor, the 5-valent Pentacel™, does not require mixing of its Haemophilus component with the four other components prior to injection; all five components are contained in one vial of vaccine. Pentacel™ was introduced shortly after Haemophilus vaccine first became available. Prior to this, polio vaccine was administered together with diphtheria, tetanus and pertussis vaccines in a 4-valent vaccine or the four vaccines were administered as a separate polio vaccine and a 3-valent DTP vaccine. It was serious adverse reactions to DTP vaccine that gave rise to much more wary vaccine consumerism starting in the 1980’s.
Pertussis deaths were rapidly declining well before the first widespread use of DTP in the late 1940s. And despite its use for more than six decades in one form or another, whooping cough outbreaks still occur in highly vaccinated populations. Long term universal vaccination with pertussis vaccines has demonstrated that immunity artificially -derived via vaccination is pathetically inept compared to immunity naturally-derived from infections. With increased vulnerability of babies of mothers who’ve never been exposed to pertussis infections, and increased vulnerability of teens and adults whose childhood vaccinations no longer protect them, pertussis vaccine is now scheduled for most of a Canadian’s lifespan. As well as Pediacel™ and Infanrix hexa™ for infants and children 2 mos to 6 yrs old, Adacel™, containing immune stimulants against tetanus, diphtheria and pertussis, is given to 12- to 54-year-olds.
Please see the separate Polio page in the Specific Vaccines section for more articles on this subject.
- The Diseases: Pertussis, Tetanus, Diphtheria, Polio and Haemophilus influenzae B
- The vaccines: PEDIACEL®, INFANRIX hexa™, and ADACEL™
- Whooping Cough: The Disease and the Vaccine By Dr. Jayne L. M. Donegan (includes history of whooping cough; risks of the vaccine; and limits to efficacy, with an emphasis on risks)
- A Not-So-Perfect Vaccine: The Diphtheria, Tetanus and Acellular Pertussis Vaccine: An Investigation (a detailed examination of pertussis disease, pertussis vaccine, and a comparison of adverse events from the whole cell pertussis vaccine with those from the newer acellular vaccine)
- The True Story of Pertussis Vaccination: A sordid Legacy? (This 2003 winner of the Jackson prize – awarded for the best article published in the 2000, 2001, and 2002 volumes of Journal of the History of Medicine and Allied Sciences – explores the history of whooping cough vaccination. See JHMAS; July 2002; 57:3 and link to NCBI PubMed.)
- Vaccine Injuries Under-Reported and Ignored (a letter to the Saskatchewan Minister of Health from parents of a young boy neurologically damaged by Pentacel™)
- Pertussis Resurgence in Canada (a science journal excerpt showing that “a poorly protective pertussis vaccine” resulted in a 10-fold increase in the incidence of pertussis)
- A Compilation of Licensed Vaccines in Canada from 1971-2003
- Haemophilus Influenza B, the Disease & the Vaccine
- Changing Disease Epidemiology Via Vaccines – Are We “Robbing Peter To Pay Paul”?
- Breastfeeding Protects from Haemophilus Influenza (medical article references)
- Diabetes Rises in Finland following Haemophilus Influenza B Vaccine (Hib)
- Tetanus – the disease and the vaccine (Dr. Sherri Tenpenny dismantles the argument that adults need Td – tetanus and diphtheria combined – shots)
- Tetanus as a single vaccine is no longer available in Canada (combination vaccines such as Pentacel™ are now the only tetanus-containing vaccines available)
- Tetanus Toxoid Vaccination (emphasizes risks and includes contraindications and alternate methods of prevention)
- Tetanus – A Compilation of Articles
- Tetanus: Dr. Mendelsohn Discusses the Disease & the Vaccine
- Magnesium as Tetanus Therapy
Links to Other Articles
- National Library of Medicine (a list of articles)
- Trends in Pertussis Among Infants in the United States, 1980-1999 (“Reported cases of pertussis among adolescents and adults have increased since the 1980’s, despite increasingly high rates of vaccination among infants and children. However, severe pertussis mobidity and mortality occur primarily among infants.”)
- Reemergence of Pertussis in the Highly Vaccinated Population of the Netherlands: Observations on Surveillance Data. (“The increase in pertussis incidence was higher among vaccinated than among unvaccinated persons of all ages. This resulted in lower estimates of vaccine effectiveness.”)

